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SciLifeLab, MAX IV and ESS tackle many questions at the atomic and molecular level!

Integrative structural biology course

InfraLife is preparing a course in integrative structural biology where we cover not only the basics of state-of-the-art structural biology techniques, but also how to combine the information to address a biological question. The course will take place in the autumn of 2022.

The two week course is a joint effort between the three large-scale research infrastructures SciLifeLab, MAX IV and ESS and additional related platforms. The aim is to give an overview of the structural biology available at the research infrastructures in Sweden. The course will focus on understanding the sample requirements, the nature of structural information that can be obtained and how data from multiple structural biology methods can be combined using e.g. computational chemistry techniques. The course consists of lectures, key note speakers, modelling practicals and facility visits. In addition events allowing time for networking within the group of students, the teachers and other infrastructure personnel, contributing to an expanded professional network.

  • *Macromolecular X-ray and neutron crystallography
  • *Small angle X-ray and neutron scattering 
  • *Cryo-electron microscopy
  • *Macromolecular nuclear magnetic resonance spectroscopy
  • *Structural mass spectrometry
  • *Modelling and Computational methods 
  • *Biophysical characterization

We proudly present a number of exciting keynote speakers that will present scientific examples of how integrative structural biology techniques can be used to solve intriguing questions.

  • Professor Poul Nissen, Aarhus University
  • Professor Carmen Domene, University of Bath
  • Postdoctoral researcher Hanna Barriga, Karolinska Institute
  • Also we will be able to join in on the SciLifeLab “Annual lecture on Structural Biology” where Dr. Demis Hassabis will talk on using AI to accelerate scientific discovery.

We will have several lectures on modelling and computational techniques for structural biology.

  • Associate professor Lucie Delemotte, Integrating physics-based and evolutionary modelling to investigate the conformational dynamics of membrane proteins
  • Professor Gunnar von Heijne, Different approaches to the study of cotranslational protein folding
  • Principal Research Engineer Claudio Mirabello, The protein structure prediction problem: from Anfinsen to AlphaFold.

English

The course is open to scientists of all age from academia, health care and industry. Level approximately corresponding to PhD student or postdoc depending on experience. Applicants welcome from Sweden, the Nordics, and other countries.

The course will be held in Sweden, on site, between Aug 22 and Sept 2nd 2022.

  • *Lund, 22 to 25 Aug
  • *Gothenburg, 26 Aug
  • *Stockholm, 29 Aug to 2 Sep


Application deadline May 23, 12pm, 2022.

Notification of acceptance June, 2022.

Applicants from academia and healthcare: 4000 SEK  
Applicants from industry: 11000 SEK

What is included in the course fee:

  • Accommodation including breakfast 3 nights in Lund, 1 night in Gothenburg and 4 nights in Stockholm
  • Transfer between Lund and Gothenburg 25/26
  • Lunch 10 days
  • Fika, twice daily, 10 days
  • Two social evening activities including food
  • One evening dinner with students and teachers
  • All lectures, practical’s and modelling sessions
  • Keynote presentations
  • Selected presentations slides

Expected from participants:

  • Travel to/from course sites in Lund and Stockholm
  • Local travel within the cities (hotel to course sites)
  • Dinners evenings without joint program
  • Computer
  • Printed Poster

After the deadline for registration a committee will decide which applicants are accepted for the course. The selection will be based on the applicants’ letter of motivation (maximum 2000 characters including spaces) that must be included in the registration. The motivation letter should declare the applicants’ research focus and what they want to gain from the different methods included in the course. We aim at having a group of selected candidates representing a good distribution in research topics and life science sectors (academia, healthcare and industry) and priority of acceptance will be given to applicants with relevant research questions. The number of participants is limited to 25 students.

A certificate will be issued after the course. PhDs are recommended to inquire with their institutions about credits. The recommendation is 10 ECTS.  

– “Offering the courser to multiple stakeholders is unique and puts further emphasis on networking and future collaborations cross sectors”, Selma Maric
– “In the long run it is very useful to learn about techniques other than you own”, Esko Oksanen.
– “Even now as a more senior researcher I would love to attend this course. I have realised the value of complementary techniques”, Michael Hall.

The organising group consists of:

OrganisationNameRole/Method
InfraLife projectJosefin Lundgren GawellCoordinator
InfraLife projectCat HalthurCoordinator
SciLifeLabDavid GottholdCoordinator
ESSEsko OksanenCrystallography
MAX IVSelma MaricSmall angle scattering
SciLifeLabCecilia PerssonNMR
SciLifeLabMarta CarroniCryo-EM
SciLifeLabMichael HallCryo-EM
SciLifeLabSimon EkströmStructural mass spectrometry
Lund UniversityLotta HapponenStructural mass spectrometry
SciLifeLabJessica LindvallCourse structure
Linköping University Maria SunnerhagenBiophysical characterisation
Linköping UniversityDean DerbyshireBiophysical characterisation

Great opportunity to sponsor and interact and present your company or organisation for the participants. If interested, please contact josefin.lundgren.gawell@scilifelab.se

This InfraLife integrative structural biology course is organized with funding support from the Swedish research council, Lif, Excillum, NBIS, Xenocs, SwedNMR, Bruker and CryoNET.

Thank you!

CryoNET